Integration and segregation manifolds in the brain ensure cognitive flexibility during tasks and rest.

ABSTRACT: Adapting to a constantly changing environment requires the human brain to flexibly switch among many demanding cognitive tasks, processing both specialized and integrated information associated with the activity in functional networks over time. In this study, we investigated the nature of the temporal alternation between segregated and integrated states in the brain during rest and six cognitive tasks using functional MRI. We employed a deep autoencoder to explore the 2D latent space associated with the segregated and integrated states. Our results show that the integrated state occupies less space in the latent space manifold compared to the segregated states. Moreover, the integrated state is characterized by lower entropy of occupancy than the segregated state, suggesting that integrat

SUBMITTER: Capouskova K 

PROVIDER: S-EPMC10681658 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature