¹⁸F-FDG PET/CT Parameters Enhance MRI Radiomics for Predicting Human Papilloma Virus Status in Oropharyngeal Squamous Cell Carcinoma.

ABSTRACT:

Purpose

Predicting human papillomavirus (HPV) status is critical in oropharyngeal squamous cell carcinoma (OPSCC) radiomics. In this study, we developed a model for HPV status prediction using magnetic resonance imaging (MRI) radiomics and ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography (PET)/computed tomography (CT) parameters in patients with OPSCC.

Materials and methods

Patients with OPSCC who underwent ¹⁸F-FDG PET/CT and contrast-enhanced MRI before treatment between January 2012 and February 2020 were enrolled. Training and test sets (3:2) were randomly selected. ¹⁸F-FDG PET/CT parameters and MRI radiomics feature were extracted. We developed three light-gradient boosting machine prediction models using the train

SUBMITTER: Jo KH 

PROVIDER: S-EPMC10681825 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature