¹⁸F-FDG PET/CT-derived total lesion glycolysis predicts abscess formation in patients with surgically confirmed infective endocarditis: Results of a retrospective study at a tertiary center.

ABSTRACT:

Background

Abnormal activity of ¹⁸F-FDG PET/CT is a major Duke criterion in the diagnostic work-up of infective prosthetic valve endocarditis (IE). We hypothesized that quantitative lesion assessment by ¹⁸F-FDG PET/CT-derived standard maximum uptake ratio (SURmax), metabolic volume (MV), and total lesion glycolysis (TLG) might be useful in distinct subgroups of IE patients (e.g. IE-related abscess formation).

Methods

All patients (n = 27) hospitalized in our tertiary IE referral medical center from January 2014 to October 2018 with preoperatively performed ¹⁸F-FDG PET/CT and surgically confirmed IE were included into this retrospective analysis.

Results

Patients with surgically confirmed abscess formation (n = 10) had significantly inc

SUBMITTER: Sag SJM 

PROVIDER: S-EPMC10682046 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature