Multi-level advances in databases related to systems pharmacology in traditional Chinese medicine: a 60-year review.

ABSTRACT: The therapeutic effects of traditional Chinese medicine (TCM) involve intricate interactions among multiple components and targets. Currently, computational approaches play a pivotal role in simulating various pharmacological processes of TCM. The application of network analysis in TCM research has provided an effective means to explain the pharmacological mechanisms underlying the actions of herbs or formulas through the lens of biological network analysis. Along with the advances of network analysis, computational science has coalesced around the core chain of TCM research: formula-herb-component-target-phenotype-ZHENG, facilitating the accumulation and organization of the extensive TCM-related data and the establishment of relevant databases. Nonetheless, recent years have witnes

SUBMITTER: Fan M 

PROVIDER: S-EPMC10682728 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature