Major adverse kidney events predict reduced survival in ventricular assist device supported patients.

ABSTRACT:

Aims

There is limited data describing major adverse kidney events (MAKE) in patients supported with ventricular assist devices (VAD). We aim to describe the association between MAKE and survival, risk factors for MAKE, and renal trajectory in VAD supported patients.

Methods and results

We conducted a single-centre retrospective analysis of consecutive VAD implants between 2010 and 2019. Baseline demographics, biochemistry, and adverse events were collected for the duration of VAD support. MAKE was defined as the first event to occur of sustained drop (>50%) in estimated glomerular filtration rate (eGFR), progression to stage V chronic kidney disease, initiation or continuation of renal replacement therapy beyond implant admission or death on renal replacement therapy at any

SUBMITTER: Barua S 

PROVIDER: S-EPMC10682875 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature