Hypoxaemic burden in heart failure patients receiving adaptive servo-ventilation.

ABSTRACT:

Aims

This study aimed to assess the effectiveness of adaptive servo-ventilation (ASV) for lowering hypoxaemic burden components in heart failure with reduced ejection fraction (HFrEF) patients.

Methods and results

Fifty-six stable HFrEF patients with left ventricular ejection fraction ≤ 40 were randomized to receive either ASV (n = 27; 25 males) or optimal medical management or optimal medical management alone (n = 29; 26 males). Patients underwent overnight polysomnography at baseline and a 12 week follow-up visit. We quantified hypoxaemic as time spent at <90% oxygen saturation (T90) decomposed into desaturation-related components (T90_desaturation ) and non-specific drifts (T90_non-specific ). In the ASV arm, T90 significantly shortened by nearly 60% f

SUBMITTER: Baumert M 

PROVIDER: S-EPMC10682887 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature