Species- and strain-level diversity of Corynebacteria isolated from human facial skin.

ABSTRACT:

Background

Sequencing of the human skin microbiome revealed that Corynebacterium is an ubiquitous and abundant bacterial genus on human skin. Shotgun sequencing further highlighted the microbial "dark matter" of the skin microbiome, consisting of microorganisms, including corynebacterial species that were not cultivated and genome-sequenced so far. In this pilot project, facial human skin swabs of 13 persons were cultivated to selectively obtain corynebacteria. 54 isolates were collected and 15 of these were genome-sequenced and the pan-genome was determined. The strains were biochemically characterized and antibiotic susceptibility testing (AST) was performed.

Results

Among the 15 sequenced strains, nine different corynebacterial species were found, including two so far und

SUBMITTER: Jensen MG 

PROVIDER: S-EPMC10683109 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature