Dataset Information

Comparison of the initial and residual speed of Ixodes scapularis kill on dogs treated with a single dose of Bravecto^® Chew (25 mg/kg fluralaner) or Simparica TRIO^® (1.2 mg/kg sarolaner, 24 µg/kg moxidectin, 5 mg/kg pyrantel).

ABSTRACT:

Background

Compliant ectoparasiticide product use is a comprehensive way to control ticks and reduce the risk of tick-borne pathogen transmission to dogs. Because the systemically acting isoxazoline ectoparasiticides require tick attachment for drug delivery, fast speed of kill is essential to minimize tick-borne pathogen transmission risk.

Methods

Dogs of satisfactory tick-carrying capacity were randomly allocated to treatment groups and administered, per label instructions, Bravecto^® Chews (minimum 25 mg/kg fluralaner), Simparica TRIO^® (minimum 1.2 mg/kg sarolaner, 24 µg/kg moxidectin, 5 mg/kg pyrantel), or no treatment. Dogs were infested with approximately 50 unfed adult (35 female, 15 male) Ixodes scapularis on Day -2, 21 and 28. Live tick counts w

SUBMITTER: Reif KE

PROVIDER: S-EPMC10683217 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature

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Dataset Information

Comparison of the initial and residual speed of Ixodes scapularis kill on dogs treated with a single dose of Bravecto^® Chew (25 mg/kg fluralaner) or Simparica TRIO^® (1.2 mg/kg sarolaner, 24 µg/kg moxidectin, 5 mg/kg pyrantel).

Background

Methods

OmicsDI is part of the ELIXIR infrastructure

Tweets

Dataset Information

Comparison of the initial and residual speed of Ixodes scapularis kill on dogs treated with a single dose of Bravecto® Chew (25 mg/kg fluralaner) or Simparica TRIO® (1.2 mg/kg sarolaner, 24 µg/kg moxidectin, 5 mg/kg pyrantel).

Background

Methods

OmicsDI is part of the ELIXIR infrastructure

Tweets

Comparison of the initial and residual speed of Ixodes scapularis kill on dogs treated with a single dose of Bravecto^® Chew (25 mg/kg fluralaner) or Simparica TRIO^® (1.2 mg/kg sarolaner, 24 µg/kg moxidectin, 5 mg/kg pyrantel).