Increasing serum miR-409-3p predicts the major adverse cardiac adverse events in elderly patients after hip fracture surgery.

ABSTRACT:

Background

Major adverse cardiovascular events (MACE) are critical complications responsible for the morbidity and mortality of elderly hip fracture patients. There was an urgent need to explore an effect biomarker for predicting MACE in elderly patients receiving hip fracture surgery.

Objective

This study focused on an age-related miRNA, miR-409-3p, and assessed its significance in elderly hip fracture patients.

Methods

A total of 267 hip fracture patients were enrolled in this study including 104 elderly patients (age ≥ 60 years). All patients were followed up for 1 year to monitor the occurrence of MACE. The risk factors for the occurrence of MACE were evaluated by the logistic regression analysis.

Results

Elderly age and reduced cardiac and renal function w

SUBMITTER: Sun Z 

PROVIDER: S-EPMC10683352 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature