Selective outcome reporting in randomised controlled trials including participants with stroke or transient ischaemic attack: A systematic review.

ABSTRACT:

Introduction

The prevalence of outcome reporting bias (ORB, i.e. selective reporting according to the results observed) across primary outcomes in randomised controlled trials (RCTs) including participants with stroke or transient ischaemic attack (TIA) is unknown.

Materials and methods

We searched the Cochrane Database of Systematic Reviews on 3 February 2021 for reviews published 2008-2020 with at least one RCT of a therapeutic intervention, for participants with stroke or TIA, and a safety or efficacy outcome. We took a random sample of these RCTs and included those with a trial registry record or protocol published before reporting results. Two reviewers assessed discrepancies in outcome reporting across the trial registry record, protocol, statistical analysis plan, and

SUBMITTER: Syed M 

PROVIDER: S-EPMC10683727 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature