Physical and brain frailty in ischaemic stroke or TIA: Shared occurrence and outcomes. A cohort study.

ABSTRACT:

Background

There is increasing interest in the concept of frailty in stroke, including both physical frailty and imaging-evidence of brain frailty. We aimed to establish the prevalence of brain frailty in stroke survivors as well as the concurrent and predictive validity of various frailty measures against long-term cognitive outcomes.

Methods

We included consecutively admitted stroke or transient ischaemic attack (TIA) survivors from participating stroke centres. Baseline CT scans were used to generate an overall brain frailty score for each participant. We measured frailty via the Rockwood frailty index, and a Fried frailty screening tool. Presence of major or minor neurocognitive disorder at 18-months following stroke or TIA was established via a multicomponent assessment

SUBMITTER: Taylor-Rowan M 

PROVIDER: S-EPMC10683729 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature