High-intensity versus moderate-intensity statin treatment for patients with ischemic stroke: Nationwide cohort study.

ABSTRACT:

Purpose

Guidelines recommend high-intensity statin treatment after ischemic stroke, but evidence is sparse on the effectiveness and safety of different statin treatment intensities. We examined effectiveness and safety outcomes among patients initiating high-intensity versus moderate-intensity statins after ischemic stroke.

Methods

In this population-based new-user active-comparator cohort study, we used the Danish Stroke Registry, covering all Danish hospitals, to identify patients with a first-time ischemic stroke during 2012-2021. Using multiple Danish registries, patients who redeemed a statin prescription within 21 days after stroke admission were classified as high-intensity statin initiators or moderate-intensity statin initiators. Propensity score inverse probability

SUBMITTER: Bach F 

PROVIDER: S-EPMC10683733 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature