Time Spent Outdoors Partly Accounts for the Effect of Education on Myopia.

ABSTRACT:

Purpose

The purpose of this study was to investigate if education contributes to the risk of myopia because educational activities typically occur indoors or because of other factors, such as prolonged near viewing.

Methods

This was a two-sample Mendelian randomization study. Participants were from the UK Biobank, Avon Longitudinal Study of Parents and Children, and Generation R. Genetic variants associated with years spent in education or time spent outdoors were used as instrumental variables. The main outcome measures were: (1) spherical equivalent refractive error attained by adulthood, and (2) risk of an early age-of-onset of spectacle wear (EAOSW), defined as an age-of-onset of 15 years or below.

Results

Time spent outdoors was found to have a small genetic comp

SUBMITTER: Clark R 

PROVIDER: S-EPMC10683767 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature