Physical Exercise and Serum BDNF Levels: Accounting for the Val66Met Polymorphism in Older Adults.

ABSTRACT:

Background

Brain-derived neurotrophic factor (BDNF) expression, which can be measured in blood serum, has been found to increase with aerobic exercise. The link between BDNF level, physical exercise, and genetic status (Val66Met polymorphism) has not been well researched in older adults.

Objective

To investigate the possible link between BDNF expression, acute aerobic exercise, and the Val66Met polymorphism in older adults.

Method

Twenty-three healthy older adults participated in one session of acute aerobic exercise. Their serum BDNF levels were measured both at baseline and post exercise. Saliva samples were collected to identify each individual's genetic status.

Results

At baseline, the individuals' mean serum BDNF level was 16.03 ng/mL (Val66Val = 15.89 ng/

SUBMITTER: Bugge Kambestad O 

PROVIDER: S-EPMC10683974 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature