Serratia marcescens enzyme SME-2 isolated from sputum in New Zealand.

ABSTRACT:

Introduction

The Serratia marcescens enzymes (SMEs) are chromosomally encoded Ambler Class A carbapenem-hydrolysing β-lactamases, which distinctively express resistance to carbapenems while remaining susceptible to extended-spectrum cephalosporins. Global reports of SMEs are infrequent. Here we describe the isolation of an SME-2-producing S. marcescens from the sputum of a patient who was hospitalized at Christchurch Hospital, New Zealand.

Methods

An immunosuppressed asthmatic patient who presented with shortness of breath and hypoxia grew S. marcescens from a sputum culture. Antimicrobial susceptibilities were determined by Phoenix, with MICs of meropenem and imipenem determined by Liofilchem^® MIC gradient strips and interpreted according to

SUBMITTER: Creighton J 

PROVIDER: S-EPMC10684264 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature