Proteomics and metabolomics analyses of Streptococcus agalactiae isolates from human and animal sources.

ABSTRACT: Streptococcus agalactiae (S. agalactiae), group B Streptococcus (GBS), a major cause of infection in a wide variety of diseases, have been compared in different human and animal sources. We aimed to compare the bacterial proteome and metabolome profiles of human and animal S. agalactiae strains to delineate biological interactions relevant to infection. With the innovative advancement in mass spectrometry, a comparative result between both strains provided a solid impression of different responses to the host. For instance, stress-related proteins (Asp23/Gls24 family envelope stress response protein and heat shock protein 70), which play a role in the survival of GBS under extreme environmental conditions or during treatment, are highly expressed in human and animal strains. One human stra

SUBMITTER: Enany S 

PROVIDER: S-EPMC10684508 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature