Combined analytical approach empowers precise spectroscopic interpretation of subcellular components of pancreatic cancer cells.

ABSTRACT: The lack of specific and sensitive early diagnostic options for pancreatic cancer (PC) results in patients being largely diagnosed with late-stage disease, thus inoperable and burdened with high mortality. Molecular spectroscopic methodologies, such as Raman or infrared spectroscopies, show promise in becoming a leader in screening for early-stage cancer diseases, including PC. However, should such technology be introduced, the identification of differentiating spectral features between various cancer types is required. This would not be possible without the precise extraction of spectra without the contamination by necrosis, inflammation, desmoplasia, or extracellular fluids such as mucous that surround tumor cells. Moreover, an efficient methodology for their interpretation has not been

SUBMITTER: Szymonski K 

PROVIDER: S-EPMC10684650 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature