Metagenomic analysis of ecological niche overlap and community collapse in microbiome dynamics.

ABSTRACT: Species utilizing the same resources often fail to coexist for extended periods of time. Such competitive exclusion mechanisms potentially underly microbiome dynamics, causing breakdowns of communities composed of species with similar genetic backgrounds of resource utilization. Although genes responsible for competitive exclusion among a small number of species have been investigated in pioneering studies, it remains a major challenge to integrate genomics and ecology for understanding stable coexistence in species-rich communities. Here, we examine whether community-scale analyses of functional gene redundancy can provide a useful platform for interpreting and predicting collapse of bacterial communities. Through 110-day time-series of experimental microbiome dynamics, we analyzed the me

SUBMITTER: Fujita H 

PROVIDER: S-EPMC10684785 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature