Survival benefit from liver transplantation for patients with and without hepatocellular carcinoma.

ABSTRACT:

Background & aims

In the USA, inequal liver transplantation (LT) access exists between patients with and without hepatocellular carcinoma (HCC). Survival benefit considers survival without and with LT and could equalise LT access. We calculated bias-corrected LT survival benefit for patients with(out) HCC who underwent a transplant, based on longitudinal data in a recent United States cohort.

Methods

Adult LT candidates with(out) HCC between 2010 and 2019 were included. Waitlist survival over time was contrasted to post-transplant survival, to estimate 5-year survival benefit from the moment of LT. Waitlist survival was modelled with a bias-corrected Cox regression, and post-transplant survival was estimated through Cox proportional hazards regression.

Results

Mean HC

SUBMITTER: Goudsmit BFJ 

PROVIDER: S-EPMC10685016 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature