Triglyceride-glucose index, renal function and cardiovascular disease: a national cohort study.

ABSTRACT:

Background

The triglyceride-glucose (TyG) index is a predictor of cardiovascular diseases; however, to what extent the TyG index is associated with cardiovascular diseases through renal function is unclear. This study aimed to evaluate the complex association of the TyG index and renal function with cardiovascular diseases using a cohort design.

Methods

This study included participants from the China Health and Retirement Longitudinal Study (CHARLS) free of cardiovascular diseases at baseline. We performed adjusted regression analyses and mediation analyses using Cox models. The TyG index was calculated as Ln [fasting triglyceride (mg/dL) × fasting glucose (mg/dL)/2]. Renal function was defined by the estimated glomerular filtration rate (eGFR).

Results

A total of 6 4

SUBMITTER: Cui C 

PROVIDER: S-EPMC10685637 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature