Individualized red-cell transfusion strategy for non-cardiac surgery in adults: a randomized controlled trial.

ABSTRACT:

Background

Red-cell transfusion is critical for surgery during the peri-operative period; however, the transfusion threshold remains controversial mainly owing to the diversity among patients. The patient's medical status should be evaluated before making a transfusion decision. Herein, we developed an individualized transfusion strategy using the West-China-Liu's Score based on the physiology of oxygen delivery/consumption balance and designed an open-label, multicenter, randomized clinical trial to verify whether it reduced red cell requirement as compared with that associated with restrictive and liberal strategies safely and effectively, providing valid evidence for peri-operative transfusion.

Methods

Patients aged >14 years undergoing elective non-cardiac surgery with e

SUBMITTER: Liao R 

PROVIDER: S-EPMC10686592 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature