Molecular epidemiology, clinical analysis, and genetic characterization of Zika virus infections in Thailand (2020-2023).

ABSTRACT: To investigate the clinical and molecular characteristics and evolution of the Zika virus (ZIKV) in Thailand from March 2020 to March 2023. In all, 751 serum samples from hospitalized patients in Bangkok and the surrounding areas were screened for ZIKV using real-time RT-PCR. Demographic data and clinical variables were evaluated. Phylogenetic and molecular clock analysis determined the genetic relationships among the ZIKV strains, emergence timing, and their molecular characteristics. Among the 90 confirmed ZIKV cases, there were no significant differences in infection prevalence when comparing age groups and sexes. Rash was strongly associated with ZIKV infection. Our ZIKV Thai isolates were categorized into two distinct clades: one was related to strains from Myanmar, Vietnam, Oceania,

SUBMITTER: Khongwichit S 

PROVIDER: S-EPMC10687007 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature