Cigarette smoking and risk of severe infectious respiratory diseases in UK adults: 12-year follow-up of UK biobank.

ABSTRACT:

Background

The relevance of tobacco smoking for infectious respiratory diseases (IRD) is uncertain. We investigated the associations of cigarette smoking with severe IRD resulting in hospitalization or death in UK adults.

Methods

We conducted a prospective study of cigarette smoking and risk of severe IRD in UK Biobank. The outcomes included pneumonia, other acute lower respiratory tract infections (OA-LRTI) and influenza. Multivariable Cox regression analyses were used to estimate hazard ratios (HRs) of severe IRD associated with smoking habits after adjusting for confounding factors.

Results

Among 341 352 participants with no prior history of major chronic diseases, there were 12 384 incident cases with pneumonia, 7054 with OA-LRTI and 795 with influenza during a 12

SUBMITTER: McGeoch LJ 

PROVIDER: S-EPMC10687597 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature