Risk of Suicide and Psychiatric Disorders Among Isotretinoin Users: A Meta-Analysis.

ABSTRACT:

Importance

Isotretinoin is hypothesized to contribute to the development of psychiatric disorders, but the epidemiological association and risk factors associated with psychiatric disorders among isotretinoin users remain unclear.

Objective

To clarify the absolute and relative risk and risk factors associated with suicide and psychiatric disorders among isotretinoin users.

Data sources

PubMed, Embase, Web of Science, and Scopus were searched from inception until January 24, 2023.

Study selection

Randomized trials and observational studies were selected if they reported the absolute risk, relative risk, and risk factors for suicide and psychiatric disorders among isotretinoin users.

Data extraction and synthesis

Relevant data were extracted and risk of bi

SUBMITTER: Tan NKW 

PROVIDER: S-EPMC10687715 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature