Electrochemical Immunosensor for the Quantification of Galectin-3 in Saliva.

ABSTRACT: Heart failure (HF) is an emerging epidemic and remains a major clinical and public health problem. Advances in the healthcare management of HF may lead to lower morbidity and mortality rates but require diagnostics to guide the process. Current diagnostics/prognostics approaches rely on expensive equipment, centralized facilities and trained personnel, marginalizing healthcare access in developing countries and rural communities. These issues have led researchers to focus on developing portable and affordable diagnostics that can be deployed at the point-of-care (POC). Typically, HF biomarkers are measured in blood not saliva. Recently, our team correlated concentrations of salivary Galectin-3 (Gal-3) to outcomes in patients with HF. We have developed an analytical device which consists of

SUBMITTER: Pittman TW 

PROVIDER: S-EPMC10688601 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature