A pilot study to assess the feasibility of a remotely monitored high-intensity interval training program prior to allogeneic hematopoietic stem cell transplantation.

ABSTRACT:

Introduction

Although allogeneic hematopoietic stem cell transplantation (HCT) can be a curative therapy for hematologic disorders, it is associated with treatment-related complications and losses in cardiorespiratory fitness and physical function. High-intensity interval training (HIIT) may be a practical way to rapidly improve cardiorespiratory fitness and physical function in the weeks prior to HCT. The primary aim of this study was to assess the feasibility of implementing a pre-HCT home-based HIIT intervention. The secondary aim was to evaluate pre to post changes in cardiorespiratory fitness and physical function following the intervention.

Methods

This was a single-arm pilot study with patients who were scheduled to undergo allogeneic HCT within six months. Patients w

SUBMITTER: Artese AL 

PROVIDER: S-EPMC10688680 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature