The impact of frontal lesions after mild to moderate traumatic brain injury on frontal network measures.

ABSTRACT: To investigate the impact of frontal macro-structural lesions on intrinsic network measures, we examined brain network function during resting-state fMRI in patients with frontal lesions in the subacute phase after mild to moderate traumatic brain injury. Additionally, network function was related to neuropsychological performances. 17 patients with frontal lesions, identified on admission CT after mild to moderate trauma, were compared to 30 traumatic brain injury patients without frontal lesions and 20 healthy controls. Three months post-injury, we acquired fMRI scans and neuropsychological assessments (measuring frontal executive functions and information processing speed). Using independent component analysis, the activity of and connectivity between network components (largely located

SUBMITTER: Rakers SE 

PROVIDER: S-EPMC10688722 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature