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The Integrated Probiotic Database: a genomic compendium of bifidobacterial health-promoting strains.


ABSTRACT: Background: The World Health Organization defines probiotics as "live microorganisms, which when administered in adequate amounts confer a health benefit on the host". In this framework, probiotic strains should be regarded as safe for human and animal consumption, i.e., they should possess the GRAS (generally recognized as safe) status, notified by the local authorities. Consistently, strains of selected Bifidobacterium species are extensively used as probiotic agents to prevent and ameliorate a broad spectrum of human and/or animal gastrointestinal disorders. Even though probiotic properties are often genus- or species-associated, strain-level differences in the genetic features conferring individual probiotic properties to commercialized bifidobacterial strains have not be

SUBMITTER: Tarracchini C 

PROVIDER: S-EPMC10688828 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature