Diffusion-weighted imaging in pediatric extracranial germ cell tumors.

ABSTRACT:

Background

Germ cell tumors (GCTs) comprise a rare and heterogeneous group of neoplasms presenting different clinical and histological characteristics, leading to a challenging scenario in clinical practice. Diffusion-weighted imaging (DWI) has been suggested as an indirect marker of tumor density and cellularity and could be used to monitor therapeutic response. However, its role in pediatric GCTs needs to be clarified.

Purpose

Here, we evaluated the features of DWI in pediatric extracranial GCTs in a reference Brazilian institution.

Material and methods

We included 43 pediatric patients with primary GCTs treated between 2008 and 2022 in Hospital de Amor de Barretos. The patients' MRI images included T1-weighted without contrast, T2-weighted, DWI and apparent diffusi

SUBMITTER: Cavalcante CEB 

PROVIDER: S-EPMC10688858 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature