Exposure to childhood maltreatment predicts adult physiological dysregulation, particularly inflammation.

ABSTRACT: Although a growing literature describes the effects of negative childhood experiences on biological outcomes, it is difficult to compare results across studies because of differences in measures of childhood experiences, biological markers, sample characteristics, and included covariates. To ensure comparability across its analyses, this study used a single national survey of adults in the United States-the Midlife in the United States (MIDUS) study-to examine comprehensively the association between adverse childhood experiences, operationalized as childhood maltreatment (CM), and biological markers of risk for poor health and to assess whether these associations differ by type of maltreatment, sex, or race. The sample included 1254, mostly White (78%), adults aged 34-86 years (mean age 57

SUBMITTER: Cornman JC 

PROVIDER: S-EPMC10688890 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature