A deep learning system for retinal vessel calibre improves cardiovascular risk prediction in Asians with chronic kidney disease.

ABSTRACT:

Backgraund

Cardiovascular disease (CVD) and mortality is elevated in chronic kidney disease (CKD). Retinal vessel calibre in retinal photographs is associated with cardiovascular risk and automated measurements may aid CVD risk prediction.

Methods

Retrospective cohort study of 860 Chinese, Malay and Indian participants aged 40-80 years with CKD [estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m²] who attended the baseline visit (2004-2011) of the Singapore Epidemiology of Eye Diseases Study. Retinal vessel calibre measurements were obtained by a deep learning system (DLS). Incident CVD [non-fatal acute myocardial infarction (MI) and stroke, and death due to MI, stroke and other CVD] in those who were free of CVD at baseline was ascertained until 31 Dec

SUBMITTER: Lim CC 

PROVIDER: S-EPMC10689182 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature