Risk of chronic kidney disease in patients with acute kidney injury following a major surgery: a US claims database analysis.

ABSTRACT:

Background

Acute kidney injury (AKI) is a common complication after major surgery. This study assessed the risk of developing or worsening of chronic kidney disease (CKD) and other clinical outcomes in patients experiencing AKI after major surgery.

Methods

This retrospective observational study used Optum's de-identified Clinformatics Data Mart Database to investigate cardiorenal outcomes in adult patients at the first AKI event following major surgery. The primary outcome was CKD stage ≥3; secondary outcomes included myocardial infarction (MI), stroke, heart failure, all-cause hospitalization, end-stage kidney disease, need for dialysis or kidney transplant and composite measures. Follow-up was up to 3 years. Additionally, the effect of intercurrent events on the risk of cl

SUBMITTER: Ohlmeier C 

PROVIDER: S-EPMC10689184 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature