The impact of gender on the risk of cardiovascular events in older adults with advanced chronic kidney disease.

ABSTRACT:

Background

Patients with chronic kidney disease (CKD) are at a higher risk of major adverse cardiovascular events (MACE) compared with the general population, but gender differences in this risk, especially in older adults, are not fully known. We aim to identify gender differences in the risk of MACE in older European CKD patients, and explore factors that may explain these differences.

Methods

The European Quality study (EQUAL) is a prospective study on stage 4-5 CKD patients, ≥65 years old, not on dialysis, from Germany, Italy, the Netherlands, Poland, Sweden and the UK. Cox regression and cumulative incidence competing risk curves were used to identify gender differences in MACE risks. Mediation analysis was used to identify variables which may explain risk differences b

SUBMITTER: Astley M 

PROVIDER: S-EPMC10689190 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature