Albuminuria and the risk of cancer: the Stockholm CREAtinine Measurements (SCREAM) project.

ABSTRACT:

Background

Studies investigating the association of chronic kidney disease and cancer have focused on estimated glomerular filtration (eGFR) rather than on albuminuria. This study aimed to examine whether albuminuria is associated with cancer incidence, and whether this association is independent of eGFR.

Methods

We included subjects of the Stockholm Creatinine Measurements (SCREAM) project without a history of cancer-250 768 subjects with at least one urine albumin-creatinine ratio (ACR) test (primary cohort) and 433 850 subjects with at least one dipstick albuminuria test (secondary cohort). Albuminuria was quantified as KDIGO albuminuria stages. The primary outcome was overall cancer incidence. Secondary outcomes were site-specific cancer incidence rates. Multivariable Co

SUBMITTER: Luo L 

PROVIDER: S-EPMC10689191 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature