Defining the window of opportunity and target populations to prevent peanut allergy.

ABSTRACT:

Background

Peanut allergy affects 1% to 2% of European children. Early introduction of peanut into the diet reduces allergy in high-risk infants.

Objective

We aimed to determine the optimal target populations and timing of introduction of peanut products to prevent peanut allergy in the general population.

Methods

Data from the Enquiring About Tolerance (EAT; n = 1303; normal risk; 3-year follow-up; ISRCTN14254740) and Learning Early About Peanut Allergy study (LEAP; n = 640; high risk; 5-year follow-up; NCT00329784) randomized controlled trials plus the Peanut Allergy Sensitization (PAS; n = 194; low and very high risk; 5-year follow-up) observational study were used to model the intervention in a general population. Peanut allergy was defined by blinded peanut chall

SUBMITTER: Roberts G 

PROVIDER: S-EPMC10689252 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature