Placebo effects in mental health disorders: protocol for an umbrella review.

ABSTRACT:

Introduction

Given the high prevalence of mental health disorders and their significant socioeconomic burden, there is a need to develop improved treatments, and to evaluate them through placebo-controlled trials. However, the magnitude of the placebo response in randomised controlled trials to test medications may be substantial, affecting their interpretation. Therefore, improved understanding of the patient, trial and mental disorder factors that influence placebo responses would inform clinical trial design to better detect active treatment effects. There is a growing literature exploring the placebo response within specific mental health disorders, but no overarching synthesis of this research has been produced to date. We present a protocol for an umbrella review of systemati

SUBMITTER: Huneke NT 

PROVIDER: S-EPMC10689367 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature