How do network meta-analyses address intransitivity when assessing certainty of evidence: a systematic survey.

ABSTRACT:

Objectives

To describe how systematic reviews with network meta-analyses (NMAs) that used the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) NMA approach addressed intransitivity when assessing certainty of evidence.

Design

Systematic survey.

Data sources

Medline, Embase and Cochrane Database of Systematic Reviews from September 2014 to October 2022.

Eligibility criteria

Systematic reviews of randomised controlled trials with aggregate data NMAs that used the GRADE NMA approach for assessing certainty of evidence.

Data extraction and synthesis

We documented how reviewers described methods for addressing intransitivity when assessing certainty of evidence, how often they rated down for intransitivity and their explanations for

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10689416 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature