Targeted V1 comodulation supports task-adaptive sensory decisions.

ABSTRACT: Sensory-guided behavior requires reliable encoding of stimulus information in neural populations, and flexible, task-specific readout. The former has been studied extensively, but the latter remains poorly understood. We introduce a theory for adaptive sensory processing based on functionally-targeted stochastic modulation. We show that responses of neurons in area V1 of monkeys performing a visual discrimination task exhibit low-dimensional, rapidly fluctuating gain modulation, which is stronger in task-informative neurons and can be used to decode from neural activity after few training trials, consistent with observed behavior. In a simulated hierarchical neural network model, such labels are learned quickly and can be used to adapt downstream readout, even after several intervening pro

SUBMITTER: Haimerl C 

PROVIDER: S-EPMC10689451 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature