Topical Atropine for Childhood Myopia Control: The Atropine Treatment Long-Term Assessment Study.

ABSTRACT:

Importance

Clinical trial results of topical atropine eye drops for childhood myopia control have shown inconsistent outcomes across short-term studies, with little long-term safety or other outcomes reported.

Objective

To report the long-term safety and outcomes of topical atropine for childhood myopia control.

Design, setting, and participants

This prospective, double-masked observational study of the Atropine for the Treatment of Myopia (ATOM) 1 and ATOM2 randomized clinical trials took place at 2 single centers and included adults reviewed in 2021 through 2022 from the ATOM1 study (atropine 1% vs placebo; 1999 through 2003) and the ATOM2 study (atropine 0.01% vs 0.1% vs 0.5%; 2006 through 2012).

Main outcome measures

Change in cycloplegic spherical equivale

SUBMITTER: Li Y 

PROVIDER: S-EPMC10690578 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature