Real-world antiseizure medication treatment outcomes in drug-resistant focal epilepsy patients.

ABSTRACT:

Objective

To gather real-world evidence on antiseizure medications (ASMs) treatment patterns and related outcomes in patients with drug-resistant focal epilepsy.

Methods

Medical insurance claims from the start of 2014 till the end of 2019 were used. Patient selection criteria included International Classification of Diseases (ICD) codes followed by documented ASM use. Baseline patient demographics along with ASM and rescue medication use patterns and related patient outcome were documented for first (index) ASM regimen. Patients who failed the first regimen and then failed the second regimen were considered drug resistant. Multivariate analyses were performed to identify risks and other characteristics for positive or negative treatment outcomes.

Results

Study cohort

SUBMITTER: Hatoum HT 

PROVIDER: S-EPMC10690664 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature