A head and neck treatment planning strategy for a CBCT-guided ring-gantry online adaptive radiotherapy system.

ABSTRACT:

Purpose

A planning strategy was developed and the utility of online-adaptation with the Ethos CBCT-guided ring-gantry adaptive radiotherapy (ART) system was evaluated using retrospective data from Head-and-neck (H&N) patients that required clinical offline adaptation during treatment.

Methods

Clinical data were used to re-plan 20 H&N patients (10 sequential boost (SEQ) with separate base and boost plans plus 10 simultaneous integrated boost (SIB)). An optimal approach, robust to online adaptation, for Ethos-initial plans using clinical goal prioritization was developed. Anatomically-derived isodose-shaping helper structures, air-density override, goals for controlling hotspot location(s), and plan normalization were investigated. Online adaptation was simulated using clinica

SUBMITTER: Nasser N 

PROVIDER: S-EPMC10691641 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature