Disseminated intravascular coagulation is strongly associated with severe acute kidney injury in patients with septic shock.

ABSTRACT:

Background

Disseminated intravascular coagulation (DIC) worsens the prognosis of septic shock and contributes to multiple organ failure. To date, no data linking DIC and acute kidney injury (AKI) occurrence, severity, and evolution in this setting are available. We aimed at analyzing the association between AKI occurrence, severity and evolution in patients with septic shock-induced DIC. In a prospective monocentric cohort study, consecutive patients, 18 years and older, admitted in the ICU of Strasbourg University Hospital in the setting of systemic hypotension requiring vasopressor related to an infection, without history of terminal chronic kidney disease were eligible. AKI was defined according to the KDIGO classification. DIC diagnosis was based on the International Society on

SUBMITTER: Helms J 

PROVIDER: S-EPMC10692023 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature