A postmortem case control study of asbestos burden in lungs of malignant mesothelioma cases.

ABSTRACT:

Background

Asbestos lung content is regarded as the most reliable tool for causal attribution of malignant mesothelioma (MM) to previous asbestos exposures. However, there is a lack of studies on asbestos burden in lungs of MM patients in comparison with healthy individuals. This study aims to provide such a comparison, investigating, as well, differences in asbestos lung burden with sex and time trends.

Methods

Asbestos lung content has been assessed on formalin-fixed lung fragments using scanning electron microscopy coupled with energy dispersion spectroscopy (SEM-EDS) on individuals deceased from MM (cases) and healthy subjects without any lung disease who died from violent causes (controls) between 2005 and 2023.

Results

Asbestos and asbestos bodies (ABs) were fou

SUBMITTER: Visona SD 

PROVIDER: S-EPMC10693031 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature