A US real-world study of treatment patterns and outcomes in localized or locally advanced prostate cancer patients.

ABSTRACT:

Purpose

Men with localized or locally advanced prostate cancer (LPC/LAPC) are at risk of progression after radiotherapy (RT) or radical prostatectomy (RP). Using real-world data, we evaluated patient characteristics, treatment patterns, and outcomes in LPC/LAPC.

Methods

Optum claims and electronic health records (EHR) data from January 2010 to December 2021 were queried for men with LPC/LAPC who received primary RT, RP, or androgen deprivation therapy alone within 180 days after diagnosis. Survival outcomes were analyzed using descriptive statistics and Kaplan-Meier curves. Real-world overall survival (rwOS) was compared in patients with and without evidence of disease (i.e., disease recurrence, metastasis, diagnosis of castration-resistant PC) at defined time points.

Res

SUBMITTER: Freedland SJ 

PROVIDER: S-EPMC10693516 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature