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Preventive strategies for low anterior resection syndrome: a protocol for systematic review and evidence mapping.


ABSTRACT:

Introduction

Rectal cancer is one of the top 10 cancers worldwide. Up to 80% of patients with rectal tumours have had sphincter-saving surgery, mainly due to the large expectation of anal preservation. However, patients tend to experience low anterior resection syndrome (LARS) after rectal resection, which is disordered bowel function that includes faecal incontinence, urgency, frequent defecation, constipation and evacuation difficulties. LARS, with an estimated prevalence of 41%, has been reported to substantially decrease the quality of life of patients. However, no comprehensive preventive strategies are currently available for LARS. This systematic review aims to synthesise evidence on the current LARS preventive strategies.

Methods and analysis

This protocol is reporte

SUBMITTER: Zhang XY 

PROVIDER: S-EPMC10693882 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature