Changes in body composition and subsequent cardiovascular disease risk among 5-year breast cancer survivors.

ABSTRACT:

Introduction

Cardiovascular disease (CVD) remains a leading cause of death in breast cancer survivors, a growing population. The aim of this study was to determine whether changes in body composition, commonly observed in breast cancer survivors, is associated with subsequent CVD risk.

Methods

This cohort study used the Korean National Health Insurance Service database. The study population included 73,271 5-year breast cancer survivors aged 40 years or above. To assess changes in body composition and its effect on the risk of CVD, validated prediction equations and multivariate Cox proportional hazards regression were used. Changes in metabolic markers (blood pressure, total cholesterol, and fasting serum glucose) according to changes in body composition were calculated by

SUBMITTER: Kim JS 

PROVIDER: S-EPMC10694451 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature