Transcriptome and proteome profile of jejunum in chickens challenged with Salmonella Typhimurium revealed the effects of dietary bilberry anthocyanin on immune function.

ABSTRACT:

Introduction

The present study investigated the effects of bilberry anthocyanin (BA) on immune function when alleviating Salmonella Typhimurium (S. Typhimurium) infection in chickens.

Methods

A total of 180 newly hatched yellow-feathered male chicks were assigned to three groups (CON, SI, and SI + BA). Birds in CON and SI were fed a basal diet, and those in SI + BA were supplemented with 100 mg/kg BA for 18 days. Birds in SI and SI + BA received 0.5 ml suspension of S. Typhimurium (2 × 10⁹ CFU/ml) by oral gavage at 14 and 16 days of age, and those in CON received equal volumes of sterile PBS.

Results

At day 18, (1) dietary BA alleviated weight loss of chickens caused by S. Typhimurium infection (P < 0.01). (2) Supplementat

SUBMITTER: Zhang S 

PROVIDER: S-EPMC10694457 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature