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Impact of population structure in the estimation of recent historical effective population size by the software GONE.


ABSTRACT:

Background

Effective population size (Ne) is a crucial parameter in conservation genetics and animal breeding. A recent method, implemented by the software GONE, has been shown to be rather accurate in estimating recent historical changes in Ne from a single sample of individuals. However, GONE estimations assume that the population being studied has remained isolated for a period of time, that is, without migration or confluence of other populations. If this occurs, the estimates of Ne can be heavily biased. In this paper, we evaluate the impact of migration and admixture on the estimates of historical Ne provided by GONE through a series of computer simulations considering several scenarios: (a) the mixture of two or more ancestral popu

SUBMITTER: Novo I 

PROVIDER: S-EPMC10694967 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature