Tumor treating fields for the treatment of glioblastoma: Current understanding and future perspectives.

ABSTRACT:

Background

This review focuses on the recently published evidence on tumor treating fields (TTFields) administered alone or in combination with locoregional and systemic options for treating glioblastoma (GBM) in the past ten years. The aim is to critically summarize the novelty and results obtained with this innovative tool, which is becoming part of the armamentarium of neurosurgeons and neuro-oncologists.

Methods

A comprehensive search and analysis were conducted on pivotal studies published in the past ten years. Furthermore, all completed clinical trials, whose results were published on clinicaltrials.gov, were examined and included in the present review, encompassing both recurrent (r) and newly diagnosed (n) GBM. Finally, an additional examination of the ongoing clini

SUBMITTER: Colamaria A 

PROVIDER: S-EPMC10695468 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature