Research diagnostic criteria for mild cognitive impairment with Lewy bodies: A systematic review and meta-analysis.

ABSTRACT:

Introduction

Operationalized research criteria for mild cognitive impairment with Lewy bodies (MCI-LB) were published in 2020. The aim of this systematic review and meta-analysis was to review the evidence for the diagnostic clinical features and biomarkers in MCI-LB set out in the criteria.

Methods

MEDLINE, PubMed, and Embase were searched on 9/28/22 for relevant articles. Articles were included if they presented original data reporting the rates of diagnostic features in MCI-LB.

Results

Fifty-seven articles were included. The meta-analysis supported the inclusion of the current clinical features in the diagnostic criteria. Evidence for striatal dopaminergic imaging and meta-iodobenzylguanidine cardiac scintigraphy, though limited, supports their inclusion. Quantitat

SUBMITTER: Donaghy PC 

PROVIDER: S-EPMC10695683 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature